Search Results - Neurodegenerative+Diseases

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Novel Peptide-Based Drugs for I.N. Delivery to Brain

Central nervous system and brain diseases impact almost 1 billion people per year with approximately 7 million related deaths worldwide. A major challenge to treating these types of diseases is the ability for therapeutics to cross the blood-brain and blood cerebrospinal barriers. These barriers make it extremely difficult to deliver therapies to the...

Published: 8/2/2019 | Inventor(s): Predrag Cudic, Jay McLaughlin

Keywords(s):

Category(s): Neurodegenerative Diseases, Drug Discovery

Bridged Bicyclic Compounds and their Derivatives as Neuroprotective Agents

This technology utilizes bridged bicyclic compounds and pharmaceutically acceptable salt forms as neuroprotective agents. The compounds have been benchmarked against resveratrol and have shown neuroprotective properties relative to it. One of the compounds provided extended time to synaptic failure by approximately 100 minutes. Additionally, another...

Published: 3/26/2021 | Inventor(s): Salvatore Lepore, Kenneth Dawson-Scully, Elijah St. Germain, Wesley Bollinger, Samantha Maki

Keywords(s):

Category(s): Neurodegenerative Diseases